Short answer: A medical obesity evaluation looks for the causes and the health effects of excess weight, not just the number on the scale. An endocrinologist checks for hormonal causes, measures body composition and waist size, and looks for diabetes, fatty liver, high blood pressure and sleep apnoea. Treatment is then planned around your health goals, and medicines such as GLP-1 injections are one option for some people, never the whole plan.

Many people in Ahmedabad now ask about weight-loss injections before they ask about anything else. That is understandable, as these medicines have changed obesity care. But the safest and most effective plans start with a careful assessment. This guide explains what that assessment involves.

Who should see an obesity specialist?

Doctors now see obesity as a chronic disease, not a lack of willpower. In 2025, a global commission described "clinical obesity", where excess body fat is already harming organs or daily life, as a condition that needs timely treatment. Indian guidelines also use lower BMI cut-offs than Western ones, because Indians develop diabetes and heart disease at lower weights. Check your BMI with the BMI calculator for Indians.

It is worth seeing a specialist if:

  • your BMI is in the obesity range for Indians, or you are overweight with diabetes, prediabetes, high blood pressure, high cholesterol, fatty liver or sleep apnoea;
  • you have tried diet and exercise seriously but the weight keeps returning;
  • you have symptoms that suggest a hormone problem, such as irregular periods, new stretch marks, or weight gain with tiredness and feeling cold;
  • you are considering weight-loss medicines and want to know whether they are right for you.

What do we check at an obesity evaluation?

An endocrinology assessment of weight usually covers five areas.

Hormonal causes

Most obesity is not caused by a single hormone problem, but some conditions must not be missed. These include an underactive thyroid, PCOS in women, and rarely, excess cortisol (Cushing's syndrome). Certain medicines, such as steroids and some psychiatric medicines, can also cause weight gain, so your medicine list matters.

Body composition and waist size

Two people with the same weight can have very different amounts of fat and muscle. Waist size is a simple marker of the harmful fat around the abdominal organs. A body composition analysis can estimate fat and muscle separately. Read waist size and health risk.

Liver

Fatty liver disease is very common in people with excess weight and often has no symptoms. Liver blood tests, and sometimes an ultrasound or a liver stiffness scan, help assess it.

Sleep apnoea

Loud snoring, pauses in breathing at night, morning headaches and daytime sleepiness can point to obstructive sleep apnoea. It is common with obesity, worsens blood pressure and sugar control, and can be tested with a sleep study.

Diabetes and heart risk

Blood tests usually include HbA1c or fasting sugar, cholesterol, kidney function and thyroid function, along with a blood pressure check.

Where do GLP-1 medicines fit?

Medicines such as semaglutide and tirzepatide act on appetite and fullness hormones. In large trials, people using them alongside lifestyle support lost substantially more weight than people on placebo. Indian guidelines suggest they can be considered for adults above certain BMI levels, especially when weight-related conditions are present.

They are not for everyone. They are avoided in pregnancy and in some medical conditions, they have side effects, and weight often returns when they are stopped. Whether a medicine is right for you, which one, and how it is started are decisions your doctor will discuss with you after the evaluation. Please do not start these medicines without a medical assessment, and avoid buying them online without a prescription.

Read more in GLP-1 medicines in India and who should consider weight-loss medicines.

How do we protect muscle during weight loss?

When weight comes down quickly, some of the loss can be muscle rather than fat. Muscle matters for strength, balance, blood sugar and long-term health, especially as we age. Enough protein in the diet and regular strength (resistance) exercise help protect it. Repeating a body composition check over time shows whether the weight being lost is mainly fat.

Read protein and muscle on weight-loss medicines.

What does follow-up look like?

Obesity is a long-term condition, so follow-up is part of the treatment. Follow-up visits usually review weight, waist size and body composition, blood tests, side effects, and how sustainable the eating and activity plan feels. The plan is adjusted over time, and the aim is lasting health, not a quick number.

When to see a doctor urgently

Seek urgent care if you have: severe or constant abdominal pain (especially spreading to the back, with or without vomiting), repeated vomiting with inability to keep fluids down, yellow eyes or skin, signs of severe dehydration such as very little urine, chest pain, fainting, or severe breathlessness. Go to the nearest emergency department immediately, or call 108 or 112.

Read more

Book a consultation with Dr. Om J Lakhani at AB Plus Hospital, Ahmedabad, or online → consult.dromlakhani.com. Call +91 73738 48848 for appointments.

References

  1. Madhu SV, et al. ESI Clinical Practice Guidelines for the Evaluation and Management of Obesity in India - An Update (2025). Indian J Endocrinol Metab. 2025. PubMed
  2. Rubino F, et al. Definition and diagnostic criteria of clinical obesity. Lancet Diabetes Endocrinol. 2025. PubMed
  3. Wilding JPH, et al. Once-Weekly Semaglutide in Adults with Overweight or Obesity. N Engl J Med. 2021. PubMed
  4. American Diabetes Association Professional Practice Committee. 8. Obesity and Weight Management for the Prevention and Treatment of Diabetes: Standards of Care in Diabetes-2026. Diabetes Care. 2026. PubMed